Qualité de vie des femmes atteintes du cancer du sein traitées dans un centre de radiothérapie à Caruaru, Pernambuco, Brésil

Jonatas Gomes Barbosa da Silva, Diogo Timóteo Costa, Iago Dillion Lima Cavalcanti, Mariane Cajubá de Britto Lira Nogueira, Diego Augusto de Oliveira

Abstract


Objectif : Déterminer la qualité de vie (QDV) des patientes atteintes du cancer du sein en traitement de radiothérapie. 

Méthodologie : La présente étude vise à mesurer, grâce à une approche quantitative descriptive, la QDV des patientes atteintes de cancer du sein traitées par radiothérapie. Un échantillon de commodité de 30 femmes en traitement de radiothérapie a répondu au questionnaire EORTC QLQ-C30 au jour 1 (1re séance de traitement) et au jour 28 (28e séance). 

Résultats : Des écarts notables dans la QDV se dégagent entre les deux collectes de données. Outre une dégradation de la santé générale (de 88,33 à 61,67) et de la santé fonctionnelle (de 76,45 à 67,77), une augmentation de l’intensité des symptômes (de 13,85 à 24,62) a été observée. 

Conclusion : Le traitement de radiothérapie nuit à la QDV des patientes atteintes du cancer du sein. L’équipe infirmière doit donc travailler en concertation avec une équipe multiprofessionnelle pour gérer adéquatement le traitement.


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Abreu, A. M. de, Fraga, D. R. da S., Giergowicz, B. B., Figueiró, R. B., & Waterkemper, R. (2021). Effectiveness of nursing interventions in preventing and treating radiotherapy side effects in cancer patients: A systematic review. Revista Da Escola de Enfermagem Da USP, 55, e03697. https://doi.org/10.1590/S1980-220X2019026303697

Akhtari, M., & Teh, B. S. (2016). Accelerated partial breast irradiation: Advances and controversies. Chinese Journal of Cancer, 35, 31. https://doi.org/10.1186/s40880-016-0095-1

Araújo, A. P. S. de, & Galvão, D. C. A. (2010). Cancêr Ósseo: Enfoque Sobre a Biologia do Câncer. Revista Saúde e Pesquisa, 3(3), 359–363.

Archangelo, S. de C. V., Neto, M. S., Veiga, D. F., Garcia, E. B., & Ferreira, L. M. (2019). Sexuality, depression and body image after breast reconstruction. Clinics, 74, e883. https://doi.org/10.6061/clinics/2019/e883

Arsenault, J., Parpia, S., Goldberg, M., Rakovitch, E., Reiter, H., Doherty, M., Lukka, H., Sussman, J., Wright, J., Julian, J., & Whelan, T. (2020). Acute toxicity and quality of life of hypofractionated radiation therapy for breast cancer. International Journal of Radiation Oncology, Biology, Physics, 107(5), 943–948. https://doi.org/10.1016/j.ijrobp.2020.03.049

Barbosa, P. A., Cesca, R. G., Pacífico, T. E. D., & Leite, I. C. G. (2017). Quality of life in women with breast cancer, after surgical intervention, in a city in the zona da mata region in Minas Gerais, Brazil. Revista Brasileira de Saúde Materno Infantil, 17(2), 385–399. https://doi.org/10.1590/1806-93042017000200010

Binotto, M., Reinert, T., Werutsky, G., Zaffaroni, F., & Schwartsmann, G. (2020). Health-related quality of life before and during chemotherapy in patients with early-stage breast cancer. Ecancermedicalscience, 14, 1007. https://doi.org/10.3332/ecancer.2020.1007

BMA, B. M. A. (2014). Pacientes e familiares. http://www.sbradioterapia.com.br

Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424. https://doi.org/10.3322/caac.21492

Brazil, M. of H. (2005). Portaria Na741, de 19 de dezembro de 2005. http://bvsms.saude.gov.br/bvs/saudelegis/sas/2005/prt0741_19_12_2005.html

Brunt, A. M., Haviland, J. S., Sydenham, M., Agrawal, R. K., Algurafi, H., Alhasso, A., Barrett-Lee, P., Bliss, P., Bloomfield, D., Bowen, J., Donovan, E., Goodman, A., Harnett, A., Hogg, M., Kumar, S., Passant, H., Quigley, M., Sherwin, L., Stewart, A., Syndikus, I., … Yarnold, J. R. (2020). Ten-year results of FAST: A randomized controlled trial of 5-fraction whole-breast radiotherapy for early breast cancer. Journal of Clinical Oncology, 38(28), 3261–3272. https://doi.org/10.1200/JCO.19.02750.

Brunt, A. M., Haviland, J. S., Wheatley, D. A., Sydenham, M. A., Alhasso, A., Bloomfield, D. J., Chan, C., Churn, M., Cleator, S., Coles, C. E., Goodman, A., Harnett, A., Hopwood, P., Kirby, A. M., Kirwan, C. C., Morris, C., Nabi, Z., Sawyer, E., Somaiah, N., FAST-Forward Trial Management Group. (2020). Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial. The Lancet, 395(10237), 1613–1626. https://doi.org/10.1016/S0140-6736(20)30932-6

Censabella, S., Claes, S., Orlandini, M., Braekers, R., Thijs, H., & Bulens, P. (2014). Retrospective study of radiotherapy-induced skin reactions in breast cancer patients: reduced incidence of moist desquamation with a hydroactive colloid gel versus dexpanthenol. European Journal of Oncology Nursing, 18(5), 499–504. https://doi.org/10.1016/j.ejon.2014.04.009.

Fayers, P. M., Aronson, N. K., Bjordal, K., Groenvold, M., Curran, D., & Bottomley, A. (2001). The EORTC QLQ-C30 Scoring Manual. Ed. European Organization for Research and Treatmente of Cancer (3rd ed.). Bruxelas.

Fontelles, M. J., Simões, M. G., Almeida, J. C. de, & Fontelles, R. G. S. (2010). Metodologia da pesquisa: diretrizes para o cálculo do tamanho da amostra. Revista Paraense de Medicina, 24(2), 57–64.

Heunis, M., Lombe, D. C., & McCaul, M. (2018). Retrospective analysis of radiotherapy outcomes in breast cancer radiotherapy at a single institution. Southern African Journal of Gynaecological Oncology, 1, 1–4. https://doi.org/10.1080/20742835.2018.1429521

Hunter, D., Mauldon, E., & Anderson, N. (2018). Cost-containment in hypofractionated radiation therapy: A literature review. Journal of Medical Radiation Sciences, 65(2), 148–157. https://doi.org/10.1002/jmrs.273

ILO, I. L. O. (2017). Minimum Wage Policy Guide. International Labour Organization. https://www.ilo.org/global/topics/wages/minimum-wages/lang--en/index.htm

Kim, S., Chukwudozie, B., & Calhoun, E. (2013). Sociodemographic characteristics, distance to the clinic, and breast cancer screening results. Journal of Health Disparities Research and Practice, 6(1), 70.

Kole, A. J., Kole, L., & Moran, M. S. (2017). Acute radiation dermatitis in breast cancer patients: challenges and solutions. Breast Cancer - Targets and Therapy, 9, 313–323. https://doi.org/10.2147/BCTT.S109763

Lievens, Y. (2010). Hypofractionated breast radiotherapy: Financial and economic consequences. The Breast, 19(3), 192–197. https://doi.org/10.1016/j.breast.2010.03.003

Lima, E. de O. L., & Silva, M. M. da. (2020). Quality of life of women with locally advanced or metastatic breast cancer. Revista Gaúcha de Enfermagem, 41, e20190292. https://doi.org/10.1590/1983-1447.2020.20190292

Linard, A. G., Silva, F. A. D. e, & Silva, R. M. da. (2002). Mulheres submetidas a tratamento para câncer de colo uterino - percepção de como enfrentam a realidade. Revista Brasileira de Cancerologia, 48(2), 493–498.

Lôbo, S. A., Fernandes, A. F. C., Fernandes, A. F. C., Almeida, P. C., Carvalho, C. M. de L., & Sawada, N. O. (2014). Quality of life in women with breast câncer undergoing chemotherapy. Acta Paulista de Enfermagem, 27(6), 554–559. https://doi.org/10.1590/1982-0194201400090

Malta, D. C., França, E., Abreu, D. M. X., Perillo, R. D., Salmen, M. C., Teixeira, R. A., … Naghavi, M. (2017). Mortality due to noncommunicable diseases in Brazil, 1990 to 2015, according to estimates from the Global Burden of Disease study. São Paulo Medical Journal, 135(3), 213–221. https://doi.org/10.1590/1516-3180.2016.0330050117

Marques, P. A. C. (2006). Pacientes com câncer em tratamento ambulatorial em um hospital privado: atitudes frente à terapia com antineoplásicos orais e lócus de controle de saúde. Universidade de São Paulo.

Marta, G. N., Coles, C., Kaidar-Person, O., Meattini, I., Hijal, T., Zissiadis, Y., … Poortmans, P. (2020). The use of moderately hypofractionated post-operative radiation therapy for breast cancer in clinical practice: A critical review. Critical Reviews in Oncology/Hematology, 156, 103090. https://doi.org/10.1016/j.critrevonc.2020.103090

Mikulandra, M., Bozina, I., & Beketic-Oreskovic, L. (2016). Radiation Therapy for Breast Cancer. Libri Oncologici, 44(2–3), 21–30.

Paterson, C., Lengacher, C. A., Donovan, K. A., Kip, K. E., & Tofthagen, C. S. (2016). Body image in younger breast cancer survivors: A systematic review. Cancer Nursing, 39(1), E39–E58. https://doi.org/10.1097/NCC.0000000000000251

Rahman, G. A., Olatoke, S. A., Agodirin, S. O., & Adeniji, K. A. (2014). Socio-demographic and clinical profile of immune-histochemically confirmed breast cancer in a resource limited country. Pan African Medical Journal, 17, 182. https://doi.org/10.11604/pamj.2014.17.182.2257

Rezaei, M., Elyasi, F., Janbabai, G., Moosazadeh, M., & Hamzehgardeshi, Z. (2016). Factors influencing body image in women with breast cancer: A comprehensive literature review. Iranian Red Crescent Medical Journal, 18(10), e39465. https://doi.org/10.5812/ircmj.39465

Rim, C. H., Ahn, S.-J., Kim, J. H., Yoon, W. S., Chun, M., Yang, D. S., … Cha, J. (2017). An assessment of quality of life for early phase after adjuvant radiotherapy in breast cancer survivors: A Korean multicenter survey (KROG 14-09). Health and Quality of Life Outcomes, 15(1), 96. https://doi.org/10.1186/s12955-017-0673-1

Rosa, D. D., Bines, J., Werutsky, G., Barrios, C. H., Cronemberger, E., Queiroz, G. S., … Simon, S. D. (2020). The impact of sociodemographic factors and health insurance coverage in the diagnosis and clinicopathological characteristics of breast cancer in Brazil: AMAZONA III study (GBECAM 0115). Breast Cancer Research and Treatment, 183(3), 749–757. https://doi.org/10.1007/s10549-020-05831-y.

Sclowitz, M. L., Menezes, A. M. B., Gigante, D. P., & Tessaro, S. (2005). Condutas na prevenção secundária do câncer de mama e fatores associados. Revista de Saúde Pública, 39(3), 340–349. https://doi.org/10.1590/S0034-89102005000300003

Sharma, N., & Purkayastha, A. (2017). Impact of radiotherapy on psychological, financial, and sexual aspects in postmastectomy carcinoma breast patients: A prospective study and management. Asia-Pacific Journal of Oncology Nursing, 4(1), 69–76. https://doi.org/10.4103/2347-5625.199075

Silveira, C. F., Regino, P. A., Soares, M. B. O., Mendes, L. C., Elias, T. C., & Silva, S. R. (2016). Quality of life and radiation toxicity in patients with gynecological and breast cancer. Escola Anna Nery, 20(4), e20160089. https://doi.org/10.5935/1414-8145.20160089

Su, J.-A., Yeh, D.-C., Chang, C.-C., Lin, T.-C., Lai, C.-H., Hu, P.-Y., … Gossop, M. (2017). Depression and family support in breast cancer patients. Neuropsychiatric Disease and Treatment, 13, 2389–2396. https://doi.org/10.2147/NDT.S135624

Swanson, W., Kamwa, F., Samba, R., Ige, T., Lasebikan, N., Mallum, A., … Ngwa, W. (2021). Hypofractionated radiotherapy in African cancer centers. Frontiers in Oncology. https://doi.org/10.3389/fonc.2020.618641

Van Hulle, H., Vakaet, V., Bultijnck, R., Deseyne, P., Schoepen, M., Van Greveling, A., Post, G., De Neve, W., Monten, C., Lievens, Y., & Veldeman, L. (2020). Health-related quality of life after accelerated breast irradiation in five fractions: A comparison with fifteen fractions. Radiotherapy and Oncology, 151, 47–55. https://doi.org/10.1016/j.radonc.2020.07.007

The WHOQOL Group (1995). The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Social Science and Medicine, 10, 1403–1409.

Xiao, C., Miller, A. H., Felger, J., Mister, D., Liu, T., & Torres, M. A. (2016). A prospective study of quality of life in breast cancer patients undergoing radiation therapy. Advances in Radiation Oncology, 1(1), 10–16. https://doi.org/10.1016/j.adro.2016.01.003

Zhang, J. J., Shu, H., Hu, S. S., Yu, Y., Sun, Y., & Lv, Y. (2018). Relationship between time elapsed since completion of radiotherapy and quality of life of patients with breast cancer. BMC Cancer, 18, 305. https://doi.org/10.1186/s12885-018-4207-y


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